| CZRC Catalog ID: |
PA7 |
| Product: |
JNK1 |
| Abbreviation: |
MAP kinase 8,MAPK 8,SAPK1c |
| Isotype: |
IgG |
| Cellular Localization: |
Cytoplasm, Nucleus |
| Antibody type: |
Rabbit Polyclonal Antibody |
| Genecard: |
Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. |
| NoteInfo: |
该抗体为CZRC与杭州华安生物技术有限公司（华安公司）合作开发，在CZRC下单订购即可享有团购价格（在线订购时请在上传汇款凭证时上传此文件）。CZRC会将有关订单转给华安公司，该抗体订单的付款、发货、售后及服务均由华安公司负责。
* 特别提醒：当您订购抗体时，勿需向CZRC进行支付；因CZRC网站有统一的订购流程，请您在“汇款凭证处”按要求上传此文件即可。 |
| Species Reactivity: |
Human,mouse,rat, Zebrafish |
| Antibody Description: |
pdf |
| Recommended Dilutions:: |
WB: 1:1,000-1:2,000 |
| Size: |
100ul liquid |
