CZRC Catalog ID: |
MA65 |
Product: |
Aldolase |
Abbreviation: |
ALDOA, ALDA |
Isotype: |
IgG |
Cellular Localization: |
Cytoplasm. |
Antibody type: |
Recombinant Rabbit Monoclonal Antibody |
Genecard: |
Fructose 1,6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1,6-bisphosphate. Fructose 1,6-bisphosphate aldolase exists as three forms: the muscle-specific Aldolase A; the liver-specific Aldolase B; and the brain-specific Aldolase C. Aldolase A, B and C arose from a common ancestral gene from which Aldo-lase B first diverged. Aldolase A is one of the most highly-conserved enzymes known, with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon, and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells. |
NoteInfo: |
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Species Reactivity: |
Human, Mouse, Rat, Zebrafish |
Antibody Description: |
pdf |
Recommended Dilutions:: |
WB: 1:500-1:2,000 ICC/IF: 1:50-1:200 IHC: 1:50-1:200 |
Size: |
100ul liquid |