| CZRC Catalog ID: |
MA52 |
| Product: |
TDP43 |
| Abbreviation: |
RNA polymerase II subunit B1, POLR2A |
| Isotype: |
IgG |
| Cellular Localization: |
Nucleus |
| Antibody type: |
Recombinant Rabbit Monoclonal Antibody |
| Genecard: |
DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR |
| NoteInfo: |
该抗体为CZRC与杭州华安生物技术有限公司（华安公司）合作开发，在CZRC下单订购即可享有团购价格（在线订购时请在上传汇款凭证时上传此文件）。CZRC会将有关订单转给华安公司，该抗体订单的付款、发货、售后及服务均由华安公司负责。
* 特别提醒：当您订购抗体时，勿需向CZRC进行支付；因CZRC网站有统一的订购流程，请您在“汇款凭证处”按要求上传此文件即可。 |
| Species Reactivity: |
Human, Mouse, Rat, Zebrafish |
| Antibody Description: |
pdf |
| Recommended Dilutions:: |
WB: 1:1,000-1:5,000 ICC: 1:100-1:500 IHC: 1:50-1:200 FC: 1:50-1:100 IP: 1:10-1:50 |
| Size: |
100ul liquid |
