CZRC Catalog ID: |
MA48 |
Product: |
ATPB |
Abbreviation: |
ATP5B |
Isotype: |
IgG |
Cellular Localization: |
Mitochondrion. Mitochondrion inner membrane. Peripheral membrane protein. |
Antibody type: |
Recombinant Rabbit Monoclonal Antibody |
Genecard: |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. |
NoteInfo: |
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Species Reactivity: |
Human, Mouse, Rat, Zebrafish |
Antibody Description: |
pdf |
Recommended Dilutions:: |
WB: 1:1,000-1:5,000 ICC: 1:100-1:500 IHC: 1:50-1:200 IP: 1:10-1:50 |
Size: |
100ul liquid |