| CZRC Catalog ID: |
MA2 |
| Product: |
Desmin |
| Abbreviation: |
DESM |
| Isotype: |
IgG |
| Cellular Localization: |
Cytoplasm |
| Antibody type: |
Rabbit Polyclonal Antibody |
| Genecard: |
Desmin is one of the earliest protein markers for muscle tissue in embryogenesis as it is detected in the somites. Although it is present early in the development of muscle cells, it is only expressed at low levels, and increases as the cell nears terminal differentiation. Desmin is also important in muscle cell architecture and structure since it connects many components of the cytoplasm. Finally, desmin may be important in mitochondria function. Desmin-related myopathy (DRM or Desminopathy) is a subgroup of the myofibrillar myopathy diseases and is the result of a mutation in the gene that codes for desmin which prevents it from forming protein filaments, instead forming aggregates of desmin and other proteins throughout the cell. Recently, mutations were identified in patients suffered by an arrhythmogenic right ventricular cardiomyopathy (ARVC). |
| NoteInfo: |
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* 特别提醒：当您订购抗体时，勿需向CZRC进行支付；因CZRC网站有统一的订购流程，请您在“汇款凭证处”按要求上传此文件即可。 |
| Species Reactivity: |
Human, mouse, Zebrafish |
| Antibody Description: |
pdf |
| Recommended Dilutions:: |
WB: 1:1,000-1:2,000 ICC: 1:200 IHC: 1:200 |
| Size: |
100ul liquid |
