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CZRC Catalog ID: CZ91
Availability: Frozen sperm
Genotype: socs1aihb29/+
Affected Gene: socs1a(socs1, zgc:91868)
Genotyping: pdf
GENOTYPE COMPOSITION
Genomic Feature Zygosity Parental Genotype Lab of Origin Construct
ihb29 homozygous Fish Developmental Biotechnology Lab
Background: AB Affectedgeneurl: unspecified Linetype: Mutant Previous Names: unspecified Background: AB Affectedgeneurl: unspecified Linetype: Mutant Previous Names: unspecified
Phenotype:
  • An upregulated expression level of gata1, an early erythroid marker, was found insocs1a/ embryos (bottom) compared with WT embryos (top) at 24 h postfertilization (hpf)
Note:
Between the 314 bp and 315 bp of the wildtype socs1a coding sequence, a cytosine(C), is inserted. The mutated socs1a codes for a protein containing 118 aa, in which only the sequence of the first 22 aa is identical to wildtype socs1a. Further MTA needed from the Fish Developmental Biotechnology Lab.
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