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CZRC Catalog ID: CZ1219
Availability: Frozen sperm
Genotype: tnfrsf1aihb319/+
Affected Gene:  tnfrsf1a
Genotyping: pdf
GENOTYPE COMPOSITION
Genomic Feature Zygosity Parental Genotype Lab of Origin Construct
ihb319 heterozygous Yonghua Sun Lab
Background: AB Affectedgeneurl: unspecified Linetype: Mutant Previous Names: TNFR1 (1), TNF Receptor 1 (TR1) (1), wu:fj65b10, zgc:85914 Background: AB Affectedgeneurl: unspecified Linetype: Mutant Previous Names: TNFR1 (1), TNF Receptor 1 (TR1) (1), wu:fj65b10, zgc:85914
Note:
Predicted to have tumor necrosis factor binding activity and tumor necrosis factor-activated receptor activity. Involved in several processes, including defense response to other organism; fin regeneration; and neutrophil chemotaxis. Predicted to localize to the membrane raft; mitochondrion; and receptor complex. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; Legionnaires' disease; acne; allergic bronchopulmonary aspergillosis; and autosomal dominant familial periodic fever. Orthologous to human TNFRSF1A (TNF receptor superfamily member 1A). 
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