国家水生生物种质资源库国家斑马鱼资源中心 (China Zebrafish Resource Center)

apoptotic process increased occurrence, eye decreased size, intestine decreased size

基准单价：

营利性：¥2600(Adults)/Unit ¥1600(Embryos)/Unit ¥6000(Frozen sperm)/Unit
非营利性：¥1300(Adults)/Unit ¥800(Embryos)/Unit ¥3000(Frozen sperm)/Unit
价格详细
友情提示：为保证传代质量，野生型种鱼不支持少量订购，10对起订。
野生型环境毒理学用鱼，20尾起订。
特别提醒：“Availability”（品系提供方式）为“Frozen Sperm”的品系仅提供由冻存精子复苏的胚胎，不支持Adult/Embryos购买，下单时请务必选择Frozen Sperm，以免订单无效，耽误您的时间。
服　　务：由国家斑马鱼资源中心发货。
* 本收费用于补助CZRC所发生的运行和人工成本。
数量：

CZRC Catalog ID:	CZ44
Availability:	Frozen sperm
Genotype:	nup107^tsu068Gt/+
Affected Gene:	nup107 (si:dkey-27k7.3, zgc:152723)
Genotyping:	pdf

GENOTYPE COMPOSITION

Genomic Feature	Zygosity	Parental Genotype	Lab of Origin	Construct
tsu068Gt	heterozygous		Meng Lab	Gt(bcl2-EGFP)

Background: AB Affectedgeneurl: unspecified Linetype: Mutant Previous Names: unspecified Background: AB Affectedgeneurl: unspecified Linetype: Mutant Previous Names: unspecified

Phenotype:

apoptotic process increased occurrence, eye decreased size, intestine decreased size

Note:

The Nup107–160 multiprotein subcomplex is essential forthe assembly of nuclear pore complexes. Homozygous nup107tsu068Gtmutant embryos exhibit tissue-specific defects after 3 days postfertilization(dpf), including loss of the pharyngeal skeletons,degeneration of the intestine, absence of the swim bladder, andsmaller eyes.In cells of the defective tissues, FGrepeatnucleoporins are disturbed and nuclear pore number isreduced, leading to impaired translocation of mRNAs from thenucleus to the cytoplasm.